Benadryl® Extra Strength Itch Stopping Cream is a topical cream formulated to provide temporary relief from minor skin itching and discomfort. It contains 2% diphenhydramine HCl, a topical analgesic, and 0.1% zinc acetate, which functions as a skin protectant. It is indicated for itching and discomfort associated with insect bites, minor burns, sunburn, minor cuts, scrapes, and skin irritations.