Neosporin Plus Pain Relief Maximum Strength First Aid Antibiotic Cream is a first-aid antibiotic cream formulated to help prevent infection while providing temporary relief from pain associated with minor cuts, scrapes, and burns. Its formula combines neomycin sulfate, polymyxin B sulfate, and pramoxine hydrochloride, with the first two ingredients providing antibiotic protection and pramoxine serving as an external analgesic.